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Considerations in Automating Cleanroom Temperature Monitoring

by Gerbig in General Cleanroom. Comments Off on Considerations in Automating Cleanroom Temperature Monitoring

Closely monitoring air temperature is necessary to prevent mold, bacterial agents, and other contaminants in your cleanroom. It is also important for any temperature-sensitive products and equipment. Automating your data equipment can bring accuracy and convenience to your process. What else do you need to know about making such a transformation?

Loggers and Sensors

Data loggers or recorders are used to record and store values like temperature, and include a range of software and hardware. They use sensors and other equipment to electronically track information. Models are available in portable, Ethernet, and wireless units. These loggers will accommodate both single and multi-channel systems.

The sensor you need will depend on your specific application, and the manufacturer will be able to help you determine this. The most common sensors are thermocouples. They’re easy and cost-effective, but they are not highly accurate. Semiconductors are … Read More »

Pharmaceutical Manufacturing: 2 Methods of Liquid Particle Counting

by Gerbig in General Cleanroom. Comments Off on Pharmaceutical Manufacturing: 2 Methods of Liquid Particle Counting

While liquids that are tested in pharmaceutical manufacturing are expected to be free from contamination, particles can enter as a result of handling and managing the water supply. Therefore, it is vital to measure particle contamination in these processes.

Particle counters are primarily used to test finished products, but a second and equally-important application is monitoring quality of water for injection.

Currently, two methods accomplish this: light obscuration and light scattering.

Light Obscuration

This method directs a laser through a narrow capillary tube with a flowing stream of liquid. Particles that pass through the beam will block light, casting shadows across the photo-detector. A calibrated particle counter determines the sizes of the particles based on how much light is blocked.

This method is best used to measure relatively large particles that are not quite visible to the naked eye. These fall into a range of … Read More »

Pros and Cons of Cleanroom Microbe Detection Devices

by Gerbig in General Cleanroom. Comments Off on Pros and Cons of Cleanroom Microbe Detection Devices

Traditional methods of detecting and correcting the presence of viable particles in a cleanroom can be lengthy. If present, viable particles can result in weeks of lost manufacturing time. However, non-traditional microbe detection significantly hastens the process of detecting and correcting the presence of viable particles. As with anything, there are downsides to these options, as well. Here is a brief comparison of options.

Traditional:

Plates. Several methods use plates that are put in areas of interest (high-risk) around the cleanroom. The plates collect particles in the air for several hours. Then the plates are collected, incubated, and after colonization, identified and counted based on the surface area of the plate. This process takes 3-7 days, during which the microorganisms will only continue to grow.
Air samplers. This is a more active means of collection, resulting in a better sample. Filter membranes, agar … Read More »

Selecting the Right Pressure Monitor for your Clean Environment

by Gerbig in General Cleanroom. Comments Off on Selecting the Right Pressure Monitor for your Clean Environment

Ideal cleanroom conditions rely on accurate pressure readings. Air in a controlled environment is not constant, so it’s critical to prevent pressure changes. This ensures that pressure won’t be so low as to allow contaminates in or so high as to waste energy.

When choosing an airflow monitor, your priorities are:

To be able to see readings at a glance
To fetch accurate readings
To catch any shift in air flow in real time
That all staff is confidently safe and protected

Therefore, in choosing the right monitoring system for your needs, keep the following in mind:

What does it take to keep the device accurate? How many hours will staff need to spend calibrating and re-calibrating the device? Make sure the device is a high enough quality that you’re confident in the accuracy of its measurements.
Fire/smoke protection. Moving from one side to the other, does the … Read More »