Pharmaceutical Package Integrity: Inspect 100% of Package Seals

Thermal imaging technology will shape the pharmaceutical industry to make package inspection thorough and precise.

Quality control standards in the pharmaceutical industry are predictably strict. Cleanroom protocols are not enough to guarantee that package seals are intact. Currently, a sampling method is used to determine package integrity. However, this is not an efficient method of quality control. The good news is that there is a far superior method on the horizon.

Dynamic thermal imaging technology has been available for some time, but it hasn’t been cost effective. Now, however, companies like Pfizer are conducting trial runs on imaging methods that, from a cost standpoint, could make thermal imaging commercially available.

Thermal imaging will deliver real-time testing of 100% of products in a line. This method doesn’t slow processes, compromise product, or interfere with production. It is a non-invasive, thorough, and portable.  The thermal imaging units can swiftly be wheeled from one packaging line to another in a matter of minutes. The best news is it is also extremely precise.

By inspecting product seals with thermal imaging, temperature changes as slight as 0.02 degrees Celsius are detected. This ensures that any breaks in the seals are caught and corrected.

The capabilities are very diverse, which means that thermal imaging offers verification of a number of types of packaging as well as fill levels. These include:

  • Plastic bottles
  • Sachets
  • Pouches
  • Stick packs
  • Blisters
  • Other flexible packaging
  • Tablet fill inspection
  • Liquid fill inspection
  • Desiccant count/inspection

This powerful technology will assist the pharmaceutical industry in cleanroom, production, and output control. The end result will yield safer products for consumers and higher profits for manufacturers.

If you have questions about cleanroom construction, verification, or certification, we are here to help you. Gerbig Engineering Company has provided expert cleanroom solutions for 30 years. We manufacture AireCell cleanrooms as well as provide verification and certification. Contact us at 888-628-0056 or

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